Cushing Syndrome

What is it?

Cushing syndrome is a condition characterized by the body’s excessive production of the hormone cortisol over a prolonged period. It can be caused by various factors, such as tumors in the pituitary gland, adrenal gland, or elsewhere in the body. The overproduction of cortisol can result from the body making too much of the hormone or due to the use of certain medications. Cushing syndrome can lead to a wide range of symptoms and complications.

What are its symptoms?

The main symptoms of Cushing syndrome include weight gain, particularly in the face, abdomen, and upper back, known as central obesity. Other common symptoms include thinning skin, easy bruising, muscle weakness, fatigue, increased thirst and urination, high blood pressure, and mood changes. Women may experience irregular menstrual periods, and men may have decreased fertility and erectile dysfunction. It’s important to note that the symptoms can vary among individuals.

What do I need to consider?

Other important facts about Cushing syndrome include the potential complications it can cause if left untreated. These may include an increased risk of infections, osteoporosis, fractures, diabetes, hypertension, cardiovascular disease, and mental health issues. Diagnosis typically involves a combination of medical history evaluation, physical examination, blood and urine tests to measure cortisol levels, imaging studies to identify potential tumors, and sometimes additional hormonal tests. Treatment options depend on the underlying cause and may include surgery, medication to suppress cortisol production, radiation therapy, or a combination of these approaches.


No file for download


  • Mayo Clinic. Cushing syndrome – Symptoms and causes. Retrieved from mayoclinic.org
  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Cushing’s Syndrome. Retrieved from niddk.nih.gov
  • Healthline. Cushing Syndrome: Signs, Causes, and Treatment. Retrieved from healthline.com
  • Cleveland Clinic. Cushing Syndrome: Causes, Symptoms & Treatment. Retrieved from [my.clevelandclinic.org](https://my